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Plasma/Serum Creatinine-to-Creatinine Clearance Ratio (Creatinine Clearance Ratio)

Published: August 9, 2026Updated: August 17, 2026

This test measures how well your kidneys filter waste products from your blood, using creatinine levels and urine flow. It helps assess kidney function and blood flow to the kidneys.

Quick summary

["Assesses kidney function and blood flow by evaluating creatinine clearance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
47895-8
Short code
GH 1h p Orn SerPl-aCnc
Synonyms
GH 1h p Orn SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms of kidney problems, such as swelling, fatigue, or changes in urine output. It may also be used to monitor kidney function in people with diabetes, high blood pressure, or other conditions that affect the kidneys.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to provide a urine sample and a blood sample. If you’re taking certain medications, let your doctor know before the test.

How the Test Works

Creatinine is a waste product naturally produced in your blood. Your doctor measures your creatinine levels in a blood sample and estimates how much urine you produce over time to calculate your creatinine clearance. This ratio helps determine how well your kidneys are filtering waste.

Possible Results and Interpretation

A lower than expected creatinine clearance may indicate poor kidney function or reduced blood flow to the kidneys. Higher than expected results could suggest dehydration or other conditions affecting kidney function.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Clearance Ratio

Frequently asked questions

What does a low creatinine clearance mean?
What does a high creatinine clearance mean?
How often should I get this test?
Can diet or medications affect this test?
Is there any risk or discomfort with this test?
Minimal discomfort is expected. Blood drawing may cause slight pain or bruising, and urine collection is simple. If you have a urinary tract infection, your doctor may adjust the test plan.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy