Skip to content

Plasma or Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function is evaluated by checking creatinine levels—higher values may indicate reduced kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47897-4
Short code
GH 1h p TRH SerPl-aCnc
Synonyms
GH 1h p TRH SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is naturally filtered out by your kidneys. If your kidneys aren’t working well, creatinine builds up in your blood. This test helps doctors monitor kidney health, especially in people with diabetes, high blood pressure, or other conditions that can affect the kidneys.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a larger blood draw. Drink plenty of water the day before to help your kidneys work normally.

What to Expect During the Test

A healthcare provider will draw blood from a vein in your arm. You may feel a slight pinch, but it usually only takes a few minutes. The blood is then sent to a lab for testing.

What the Results Mean

Results are compared to a general reference range, but individual values can vary based on age, sex, muscle mass, and overall health. High levels may signal kidney problems, while very low levels could indicate muscle disorders or other conditions.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health history, symptoms, and other tests. For example, people with diabetes or kidney disease may need it more frequently than others.
Can diet or exercise affect my creatinine levels?
Yes, diet and exercise can influence creatinine levels. Eating high-protein foods or intense exercise may temporarily raise levels, but your body usually balances them out. Hydration is key—drinking enough water helps your kidneys filter creatinine properly.
What if my results are outside the normal range?
If your results are higher than expected, your doctor may recommend follow-up tests, lifestyle changes, or treatments to support kidney health. If results are lower, they may investigate other potential causes, such as muscle loss or certain medications.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy