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Serum/plasma mass concentration of aldosterone (measured via mass spectrometry)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of aldosterone, a hormone that helps regulate blood pressure and fluid balance in your body.

Quick summary

["Aldosterone helps control how much sodium and potassium your body retains, which affects your blood pressure and fluid levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27369-8
Short code
GH 2.5h p chal SerPl-mCnc
Synonyms
GH 2.5h p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to diagnose or monitor conditions like primary aldosteroneism (a rare disorder causing high blood pressure), adrenal gland issues, or to check for hormonal imbalances that affect blood pressure or kidney function. It may also be used in patients with hypertension (high blood pressure) who don’t respond well to usual treatments.

What Does a High or Low Level Mean?

High aldosterone levels may indicate conditions such as aldosteroneism, kidney disease, or certain medications that affect hormone balance. Low levels could suggest adrenal insufficiency or other hormonal disorders. Your doctor will interpret results in the context of your overall health and symptoms.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The sample is collected in a special tube that separates serum or plasma from blood cells. This test is typically done after fasting for 8–12 hours, depending on your doctor’s instructions.

What to Expect Before the Test

There are no special preparations needed beyond following your doctor’s instructions. Avoid smoking or consuming caffeine for a few hours before the test if advised. Wear comfortable clothing and plan to rest after the blood draw.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Aldosterone plays a critical role in maintaining electrolyte balance and blood pressure. Abnormal levels can lead to complications such as high blood pressure, kidney problems, or fluid imbalances. This test helps identify conditions that may require treatment, such as hormone therapy or medication adjustments to manage symptoms.

Short name

Aldosterone level

Frequently asked questions

How long does it take to get results?
Results are usually available within 1–3 business days, depending on your lab’s processing time. Your doctor will contact you with the final report once it’s ready.
What are common causes of high aldosterone levels?
Common causes include primary aldosteroneism (a genetic or autoimmune condition), kidney diseases, certain medications (like steroids or NSAIDs), and conditions like Conn’s syndrome. Lifestyle factors like obesity or high salt intake may also play a role.
Can I eat or drink before this test?
Yes, but typically you’ll need to fast for 8–12 hours before the test unless your doctor specifies otherwise. Follow their instructions carefully to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy