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Serum or Plasma Substance Concentration (Mass) – Aldosterone

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of aldosterone, a hormone produced by your adrenal glands that helps regulate blood pressure and fluid balance.

Quick summary

["Aldosterone helps control how much salt and water your body retains, which can affect your blood pressure and heart health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12701-9
Short code
GH 2.5h p chal SerPl-sCnc
Synonyms
GH 2.5h p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like high blood pressure, low potassium levels, or signs of conditions like primary aldosteronism (a rare disorder affecting hormone production). It may also be used to monitor certain kidney or adrenal gland disorders.

What to Expect Before the Test

No special preparation is usually needed, but your doctor might advise you to avoid certain medications (like some blood pressure drugs) or limit salt intake for a few days before testing. You’ll provide a blood sample drawn from a vein in your arm.

What the Results Mean

Results help determine if your aldosterone levels are too high or low, which can guide treatment for conditions like hypertension or adrenal issues. Your doctor will compare these results to your symptoms and other test findings.

Common Conditions Monitored

High aldosterone levels may be linked to conditions like primary aldosteronism, kidney disease, or certain medications. Low levels could suggest adrenal insufficiency or other hormonal imbalances.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Elevated aldosterone is often associated with secondary hypertension or hyperaldosteronism, which can lead to complications like heart strain or kidney damage. Low levels may indicate adrenal gland dysfunction or other endocrine disorders requiring further evaluation.

Short name

Aldosterone (Serum/Plasma)

Frequently asked questions

How is aldosterone tested?
This test measures aldosterone in your blood, typically drawn from a vein. The sample is sent to a lab for analysis using a sensitive immunoassay method to detect the hormone’s concentration.
What are typical reference ranges?
Reference ranges vary by lab and can depend on factors like age, sex, and health status. Your doctor will provide your specific results and compare them to your individual baseline.
Can diet affect aldosterone levels?
Yes, high sodium intake or certain medications (like steroids or diuretics) can influence aldosterone levels. Your doctor may recommend dietary adjustments or medication changes before testing if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy