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Glucose, Plasma (24-hour average)

Published: August 9, 2026Updated: August 17, 2026

This test measures the average level of glucose (sugar) in your plasma over a 24-hour period, helping doctors assess how well your body manages blood sugar levels.

Quick summary

["Understanding your body’s natural glucose balance over time can help prevent complications from high or low blood sugar."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
55513-6
Short code
GH 30M p CLN SerPl-mCnc
Synonyms
GH 30M p CLN SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order a 24-hour plasma glucose profile to evaluate how your body handles glucose, especially if you have diabetes, prediabetes, or symptoms like frequent hunger, fatigue, or unexplained weight changes. It can also help check for conditions like reactive hypoglycemia or insulin resistance.

How the Test Works

Blood is collected at specific times throughout the day (typically every 2–4 hours) to measure glucose levels in plasma. The results are averaged to provide a comprehensive picture of your glucose control.

What to Expect Before the Test

You’ll need to fast (not eat or drink anything except water) for 8–12 hours before the test. Follow your doctor’s instructions carefully to ensure accurate results. Wear comfortable clothing and plan for multiple blood draws during the day.

What to Expect During the Test

Blood samples are drawn from a vein in your arm at scheduled intervals. You may feel a slight pinch or discomfort, but it usually lasts only a few seconds. You’ll be able to eat and drink normally after the fasting period.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Plasma Glucose Profile

Frequently asked questions

A 24-hour plasma glucose profile helps identify patterns in blood sugar that standard single-point tests might miss. For example, it can detect whether your glucose levels spike after meals or drop too low between meals, guiding treatment plans for diabetes or other metabolic conditions.
This test is not a replacement for regular blood sugar monitoring but provides deeper insight into how your body manages glucose over time.
How long will I need to prepare for this test?
You’ll need to fast for 8–12 hours before the first blood draw, and you may need to stay in for the full 24-hour period to collect samples at scheduled times. Your doctor will provide exact instructions.
Will I need to take any special medications or supplements before the test?
Ask your doctor about any medications or supplements you’re taking, especially those that affect blood sugar. Some may need to be adjusted or temporarily paused before the test to avoid interfering with results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy