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Growth Hormone (Serum) – Mass Concentration, 24-Hour Profile

Published: August 9, 2026Updated: August 17, 2026

This test measures your body’s natural growth hormone levels over a 24-hour period to help diagnose conditions like growth hormone deficiency or excess.

Quick summary

["Assesses long-term hormone activity to guide treatment decisions for growth-related disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
95850-4
Short code
GH 30M p Macimorelin Ser IA-mCnc
Synonyms
GH 30M p Macimorelin Ser IA-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order a 24-hour growth hormone profile if you have symptoms like slow growth in children, muscle weakness, or unexplained weight changes in adults. It helps determine whether your body produces enough growth hormone or if it’s working too much.

How the Test Works

Blood samples are collected at multiple times (typically every 20–30 minutes) over 24 hours to track hormone fluctuations. The results help identify patterns in hormone release, which can guide treatment plans.

Sample Collection Process

You’ll need to stay at a clinic or hospital for the full 24 hours. A healthcare provider will draw blood at scheduled intervals while you rest or go about normal activities. Avoid strenuous exercise or certain foods/drinks that may affect results.

What to Expect Before the Test

No special preparation is needed beyond following your usual diet and activity routine. If you’re on medications, ask your doctor to confirm if any adjustments are needed before the test.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

24-Hour Growth Hormone Profile

Frequently asked questions

This test helps diagnose growth hormone deficiency (too little hormone) or acromegaly (too much hormone) by showing abnormal hormone levels over time. It’s also used to monitor treatment effectiveness for conditions like pituitary tumors or genetic disorders.
A 24-hour profile is more accurate than single-point measurements because growth hormone levels naturally rise and fall throughout the day, especially during sleep.
What are the typical symptoms that might lead to this test?
Symptoms like slow growth in children, excessive sweating, joint pain, or unexplained weight gain in adults may prompt this test. Doctors also use it to evaluate unexplained muscle weakness or metabolic issues.
How long does it take to get results?
Results are usually available within 1–2 weeks, depending on lab processing times. Your doctor will discuss them with you during a follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy