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Propranolol in Serum (Quantitative Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of propranolol, a medication used to treat high blood pressure, heart rhythm disorders, and anxiety, in your blood.

Quick summary

["Knowing your propranolol levels helps your doctor monitor your dose and ensure it’s working safely."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48130-9
Short code
GH 30M pre propranolol+Gc SerPl-aCnc
Synonyms
GH 30M pre propranolol+Gc SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking propranolol to check if your dose is appropriate. It can also help detect drug interactions or side effects, such as low blood pressure or unusual fatigue.

What to Expect Before the Test

No special preparation is needed, but avoid eating or drinking anything (except water) for 2 hours before the blood draw. Fasted or non-fasted results may be reported differently.

What the Test Results Mean

Results are typically reported in micrograms per milliliter (mcg/mL). High levels may indicate overdose or poor metabolism, while low levels could mean your dose isn’t sufficient.

Common Reasons for Abnormal Results

Elevated levels might suggest drug toxicity, liver issues, or improper dosing. Low levels could mean the medication isn’t absorbing well or you’re not taking it as prescribed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Monitoring Medication Effectiveness

Frequently asked questions

How often should I get this test?
Your doctor will determine the frequency based on your treatment plan, but typically, it’s done every few months or as needed to adjust your dose.
Can diet or other medications affect this test?
Yes, grapefruit or grapefruit juice can increase propranolol levels. Other medications (like certain antidepressants or heart medications) may also interact, so always inform your doctor of all medications you take.
What symptoms should I watch for if my levels are off?
High levels may cause dizziness, slow heartbeat, or breathing difficulties. Low levels might lead to irregular heartbeat, high blood pressure, or anxiety. Seek medical attention if you experience these symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy