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Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your plasma. It helps assess kidney function.

Quick summary

["Kidney health and filtering ability can be evaluated with this simple blood test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48131-7
Short code
GH 30M pre TRH SerPl-aCnc
Synonyms
GH 30M pre TRH SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check how well your kidneys are working, monitor kidney disease, or evaluate symptoms like fatigue, swelling, or changes in urine output. It’s often used alongside other tests to diagnose conditions like chronic kidney disease or acute kidney injury.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic panel. Drink plenty of water the day before to ensure your kidneys are functioning normally.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm. You may feel a slight pinch, but it usually takes only a few minutes. The blood sample is sent to a lab for analysis.

What Are the Results Mean?

Results help determine if your kidneys are filtering waste properly. Abnormally high or low levels may signal kidney problems, but interpretation depends on your overall health and other test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High creatinine levels may indicate reduced kidney function, while persistently low levels could suggest overhydration or muscle disorders. Regular monitoring is critical for patients with diabetes, hypertension, or a history of kidney issues, as creatinine helps track progression and guide treatment adjustments.

Short name

Creatinine Level

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health status. For example, people with kidney disease may need it monthly or more frequently, while healthy individuals might only need it annually or as part of routine check-ups.
What causes creatinine levels to be too high?
High creatinine levels can result from kidney disease, dehydration, severe muscle damage, or conditions that impair blood flow to the kidneys. Chronic conditions like diabetes or heart disease may also contribute.
What if my creatinine level is abnormal?
If your results are outside the expected range, your doctor will discuss next steps, which may include additional tests (like blood urea nitrogen or imaging), lifestyle changes, or medications to support kidney health. Follow-up visits will help track progress.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy