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Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess kidney function.

Quick summary

["A creatinine test helps doctors check how well your kidneys are filtering waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49953-3
Short code
GH 3:30 AM SerPl-aCnc
Synonyms
GH 3:30 AM SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out by your kidneys. High levels can indicate kidney problems, while low levels might suggest dehydration or muscle loss. This test is often used alongside other kidney function tests to monitor overall kidney health, especially in people with diabetes, high blood pressure, or other chronic conditions.

How the Test Works

A small blood sample is drawn from your arm. The sample is then analyzed to measure the concentration of creatinine in your plasma. The test does not require fasting unless specified by your healthcare provider.

What to Expect Before the Test

There are usually no special preparations needed for this test. However, if you are on a low-protein diet or have recently exercised heavily, your results might be affected. Always follow your doctor’s instructions for any pre-test guidelines.

What to Expect During the Test

You will lie down comfortably while a healthcare professional inserts a needle into your arm to draw a small amount of blood. The process is quick and typically causes only minor discomfort. You may feel a slight pinch or sting, but most people find it tolerable.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

How does a creatinine test help doctors?
Doctors use creatinine levels to estimate how well your kidneys are working. Higher than normal levels may signal kidney damage or disease, while persistently low levels could indicate conditions like dehydration or muscle wasting. Regular monitoring of creatinine levels is crucial for managing chronic kidney disease, heart conditions, or other health issues that affect kidney function.
What does it mean if my creatinine level is high?
A high creatinine level may suggest that your kidneys are not filtering waste properly, which could be due to kidney disease, dehydration, or other health conditions. Your doctor will consider your overall health, other test results, and symptoms to determine the cause and next steps.
Can diet affect my creatinine test results?
Yes, diet can influence creatinine levels. High-protein foods or intense exercise can temporarily increase creatinine levels. If you have dietary restrictions or concerns, discuss them with your healthcare provider before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy