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Glucose in Serum (24-hour urinary collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of glucose excreted in your urine over a 24-hour period, which can help assess how well your body regulates blood sugar levels.

Quick summary

["Helps identify urinary glucose loss, often linked to diabetes or kidney issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
79180-6
Short code
GH 45M p chal SerPl-aCnc
Synonyms
GH 45M p chal SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if they suspect you have conditions like diabetes, kidney disease, or other metabolic disorders that affect glucose handling. It’s particularly useful for detecting excessive glucose loss in urine, which can occur in certain genetic or chronic conditions.

How the Test Works

You’ll collect all your urine over 24 hours in a special container. The sample is then analyzed to determine the total glucose content, which is compared to standard values to identify abnormalities.

What to Expect Before the Test

No special preparation is needed beyond collecting all urine for the full 24-hour period. Drink as usual, but avoid diuretics or medications that may affect urine glucose levels unless instructed otherwise.

What to Expect During the Test

You’ll provide a single urine sample after completing the 24-hour collection. The lab processes this sample to measure glucose concentration, often using automated methods like enzymatic assays.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urinary Glucose

Frequently asked questions

What does a high urinary glucose level mean?
A high urinary glucose level may indicate your body isn’t properly regulating blood sugar, which could be due to diabetes, kidney issues, or other metabolic disorders. Your doctor will discuss results in the context of your symptoms and medical history.
How is this test different from a standard blood glucose test?
Unlike blood glucose tests (e.g., fasting or random plasma glucose), this test measures glucose lost in urine over 24 hours, giving a broader picture of how your body handles glucose beyond just blood levels. It’s particularly useful for detecting urinary glucose loss that isn’t reflected in blood tests alone.
Can I eat or drink normally before this test?
Yes, you can eat and drink as usual, but avoid medications or supplements that might affect urine glucose levels unless your doctor advises otherwise. The key is collecting *all* urine for the full 24-hour period.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy