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Serum or plasma mass concentration of glucose (24-hour urinary collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of glucose (sugar) excreted in your urine over a 24-hour period. It helps assess how much sugar your body is filtering through the kidneys.

Quick summary

["Helps track long-term sugar levels and kidney function in diabetes management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29151-8
Short code
GH 4h p chal SerPl-mCnc
Synonyms
GH 4h p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters in Diabetes Care

While blood glucose tests show your current sugar levels, this test provides a broader picture of your body’s overall sugar handling over time. High urinary glucose can indicate poor kidney function or uncontrolled diabetes, while low levels may suggest malabsorption or other metabolic issues.

How the Test Works

Your doctor will collect a 24-hour urine sample, typically starting after an initial void (empty bladder). You’ll collect all urine for 24 hours, storing it in a refrigerator. The sample is then analyzed to measure total glucose content.

What to Expect Before the Test

No special preparation is needed, but drink plenty of water to ensure normal urine flow. Avoid excessive sugar intake on the day of collection if instructed by your provider.

Common Causes of Abnormal Results

Elevated levels may signal diabetes, kidney disease, or excessive sugar intake. Low levels could indicate conditions like diabetes insipidus or malabsorption syndromes. Always discuss results with your healthcare team.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Glucose (Total)

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have diabetes, kidney disease, or symptoms like frequent urination, excessive thirst, or unexplained weight changes. It helps track how well your body is managing sugar and filtering waste.
What does a high or low result mean?
A high result may mean your kidneys aren’t working well, or your diabetes isn’t under control. A low result could indicate problems with sugar absorption or other metabolic issues. Your provider will interpret results in the context of your overall health.
Do I need to fast before this test?
No fasting is required. However, follow your provider’s instructions for proper urine collection to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy