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Serum or plasma mass concentration of a specific protein (e.g., albumin, globulin, or other protein marker)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a particular protein in your blood, either in serum or plasma, using mass concentration techniques.

Quick summary

["Understanding your protein levels can help identify potential health concerns or monitor existing conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29152-6
Short code
GH 5h p chal SerPl-mCnc
Synonyms
GH 5h p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if they suspect issues like protein loss, kidney disease, liver problems, or certain infections. It could also be used to monitor chronic conditions or track responses to treatments.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours if the test involves fasting-related protein measurements. Bring any medications or allergies to your appointment.

During the Test Process

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the procedure is quick. The sample is then processed to measure the protein concentration accurately.

What the Results Mean

Results compare your protein levels to standard ranges for your age and health status. Abnormal levels may signal conditions like malnutrition, inflammation, or organ dysfunction. Your provider will discuss findings with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How common is this test, and who typically gets it?
This test is widely used in routine and specialized medical evaluations, especially in diagnosing or monitoring conditions affecting protein metabolism. It’s often paired with other tests depending on your symptoms or medical history.
What does it cost, and is insurance covered?
Costs vary by lab, location, and insurance coverage. Many insurance plans cover routine blood tests, but confirm with your provider for specifics. Out-of-pocket costs may apply for additional testing or follow-ups.
Can I fast before this test?
Fasting may be required for certain protein-related tests (e.g., albumin), but check with your lab or provider first. Non-fasting tests (like globulin) usually don’t require fasting, but always follow their instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy