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Glucose in plasma (24-hour urine collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures how much glucose (sugar) appears in your urine over a 24-hour period, which can help assess how well your body manages blood sugar levels.

Quick summary

["This test helps detect excessive sugar in urine, often linked to diabetes or other metabolic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49958-2
Short code
GH 6 AM SerPl-aCnc
Synonyms
GH 6 AM SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like frequent urination, excessive thirst, or unexplained weight changes. It’s also used to monitor blood sugar control in people with diabetes or suspected metabolic disorders.

What to Expect Before the Test

You’ll need to collect all urine for 24 hours (typically from one morning to the next morning). Drink plenty of water to help flush out glucose, but avoid sugary drinks or foods. Follow your provider’s instructions precisely to ensure accurate results.

How the Test Works

The collected urine is analyzed to measure the total amount of glucose excreted. This is done using a specialized lab method that detects glucose presence and quantifies it in the urine sample.

What the Results Mean

High levels of glucose in urine may indicate diabetes, kidney issues, or other conditions affecting sugar metabolism. Low or absent glucose in urine usually means your body is handling sugar normally.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated urine glucose is often a key indicator of diabetes mellitus, where the body struggles to regulate blood sugar. It can also signal other conditions like gestational diabetes, kidney problems, or hormonal imbalances. Regular monitoring helps manage these conditions effectively and prevent complications.

Short name

Urine Glucose Profile

Frequently asked questions

What causes high urine glucose levels?
High urine glucose can result from diabetes (both type 1 and type 2), poor blood sugar control, kidney issues, or certain medications. Stress, illness, or hormonal changes may also temporarily increase glucose excretion.
How is this test different from a standard blood glucose test?
Unlike a blood glucose test, which measures sugar levels in your bloodstream, this test checks for sugar in your urine over a full day. It’s useful for assessing long-term sugar handling and detecting glucose leaks that might not appear in blood tests.
Can I take medications before this test?
Most medications can be taken as usual unless your provider advises otherwise. However, avoid sugary supplements or drinks during the urine collection period to prevent false results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy