Skip to content

Serum or plasma mass concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. It helps assess liver function and detect conditions like jaundice or bile duct blockages.

Quick summary

["Total bilirubin levels can signal liver or bile system issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63560-7
Short code
GH 8.5h p chal SerPl-mCnc
Synonyms
GH 8.5h p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for liver problems, such as hepatitis, cirrhosis, or gallstones, which can affect how bilirubin is processed. It’s also used to monitor conditions like hemolytic anemia (where red blood cells break down too quickly) or to evaluate bile duct blockages that could prevent bilirubin from leaving the body normally.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a liver function panel. Bring any medications you’re taking, as some (like certain pain relievers) can influence results.

During the Test

A small blood sample will be drawn from a vein, usually in your arm. You may feel a slight pinch, but it’s quick and shouldn’t cause discomfort. If you’re nervous, let your provider know—they can use a tourniquet or distraction techniques.

After the Test

You can return to your normal activities immediately. Apply gentle pressure to the site to stop any bleeding, and check for signs of infection (like redness or swelling) over the next few days. Avoid rubbing the area too hard.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated bilirubin levels often point to liver or bile duct issues, such as jaundice (yellowing of skin/hair), where bilirubin builds up because the liver isn’t processing it properly. Low levels may indicate liver disease or other conditions affecting red blood cell breakdown. Always discuss results with your provider—they’ll interpret them in the context of your overall health.

Short name

Total bilirubin

Frequently asked questions

What causes abnormal bilirubin levels?
Abnormal levels can result from liver disease, bile duct problems, or conditions like hemolytic anemia (where red blood cells break down too quickly). Other factors, such as certain medications or genetic disorders, may also play a role.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your provider will explain them in detail during your follow-up visit.
Can diet affect bilirubin test results?
Diet alone rarely affects bilirubin levels, but certain foods (like excessive alcohol or high-fiber diets) may indirectly influence liver function. Avoiding alcohol before testing is recommended to prevent false elevations.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy