C-reactive protein (CRP) mass concentration in serum/plasma
This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in the body.
["CRP helps identify and monitor inflammation, often used to assess infection, injury, or autoimmune conditions."]
Key facts at a glance
- LOINC
- 56565-5
- Short code
- GH 9h p chal SerPl-mCnc
- Synonyms
- GH 9h p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Doctors may order CRP tests to check for signs of inflammation, monitor chronic conditions like rheumatoid arthritis or lupus, or evaluate symptoms such as fever, pain, or swelling that could indicate infection, injury, or other health issues. It’s also used in some risk assessments for heart disease.
What Does a High CRP Level Mean?
Elevated CRP levels often signal inflammation. While high levels can point to infections (like pneumonia or urinary tract infections), they may also appear in conditions like heart disease, certain cancers, or autoimmune diseases. Your doctor will consider your symptoms and other test results to interpret the results.
What Does a Low CRP Level Mean?
Low CRP levels typically mean there is little to no active inflammation in your body. However, very low levels might raise concerns if you have a chronic condition that usually requires monitoring CRP, so always discuss results with your healthcare provider.
How Is This Test Performed?
A blood sample is taken from a vein, usually in your arm. The blood is then sent to a lab where it is processed to separate serum or plasma. The CRP protein is measured using a sensitive lab technique to detect its concentration.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CRP (Serum/Plasma)
Frequently asked questions
What causes CRP levels to be high?
What should I do if my CRP test is abnormal?
Can CRP levels change over time?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy