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Glucose (Plasma) Following Clonidine Stimulation

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood sugar level after taking a medication called clonidine to check how your body responds to stress or certain medications.

Quick summary

["Assesses how your body manages blood sugar under controlled stress conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92666-7
Short code
GH + glucose p cloNIDine stim pnl SerPl
Synonyms
GH + glucose p cloNIDine stim pnl SerPl
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to evaluate how your body handles blood sugar changes, especially if you have conditions like diabetes or are taking medications that affect blood sugar. It can also help diagnose or monitor certain hormonal or metabolic disorders.

What to Expect Before the Test

You’ll likely fast for several hours before the test. Your blood will be drawn after you take a clonidine pill or patch to stimulate your body’s response. Avoid eating or drinking anything except water for the fasting period.

During the Test

A healthcare provider will draw blood from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The test itself is quick, and you can return to normal activities afterward.

After the Test

You can eat and drink normally after fasting is complete. If you experience any unusual symptoms like dizziness or low blood sugar, contact your doctor immediately.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps identify how your body responds to stress-induced blood sugar changes, which can be critical in diagnosing conditions like diabetes, adrenal disorders, or reactions to medications. Abnormal results may indicate issues with insulin production, metabolism, or stress responses.

Short name

Clonidine-Stimulated Plasma Glucose

Frequently asked questions

How is this test different from a regular blood sugar test?
Unlike standard blood sugar tests (like fasting or random glucose), this test measures your response to clonidine, which mimics stress. It helps assess how your body manages blood sugar under controlled conditions, often used in specific diagnostic scenarios.
What does a high or low result mean?
High results may suggest your body struggles to regulate blood sugar, possibly due to diabetes, adrenal problems, or medication effects. Low results could indicate hypoglycemia or an overactive stress response. Your doctor will interpret results in the context of your overall health.
Do I need to prepare differently if I’m on diabetes medication?
Yes, inform your doctor about all medications, including diabetes drugs, insulin, or clonidine. They may adjust your treatment plan based on the test results to avoid complications.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy