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Glucose in Serum or Plasma (24-Hour Profile)

Published: August 9, 2026Updated: August 17, 2026

This test measures your blood glucose levels over a 24-hour period using a sample of your serum or plasma. It helps track how your body responds to food, activity, and other factors over time.

Quick summary

["Understanding how your glucose levels fluctuate throughout the day can help manage conditions like diabetes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
47936-0
Short code
GH pre Orn SerPl-aCnc
Synonyms
GH pre Orn SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have diabetes or are at risk of developing it. It can also help assess how well your current treatment plan is working or identify patterns in your glucose levels that might need adjustment.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a portion of the 24-hour period (e.g., overnight fasting before collecting morning samples). Bring a diary or tracker to note your food, activity, and any symptoms during the test.

How the Test Is Collected

Blood samples are collected at scheduled times (often including morning, afternoon, and evening) using a small needle. Urine or other fluid samples may also be collected if specified. The samples are sent to a lab for analysis.

What the Results Mean

Results show your glucose levels at different times. High or low readings at specific times may indicate how your body processes glucose, which can help guide treatment decisions. Your provider will interpret the results in the context of your health and symptoms.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Glucose Monitoring

Frequently asked questions

How often should I get this test?
This test is typically done once or twice a year for people with diabetes to monitor trends in glucose control. If you don’t have diabetes but have risk factors (e.g., obesity, family history), your provider may recommend it less frequently or at different intervals.
What do I do if my glucose levels are consistently high or low?
Consistently high or low glucose levels warrant discussion with your healthcare provider. They may adjust your treatment plan, including medications, diet, or lifestyle changes, to help stabilize your levels. Never adjust your treatment without professional guidance.
Can I eat or drink anything before the scheduled blood draws?
Yes, but follow your provider’s instructions. Some samples may require fasting (e.g., overnight), while others may allow small sips of water or snacks. Always check with your lab or provider before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy