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Glucose in Serum/Plasma (24-Hour Profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood glucose levels over a 24-hour period using a sample of your serum or plasma. It helps assess how your body manages glucose, which is important for understanding diabetes control or metabolic health.

Quick summary

["This test helps doctors check how well your body regulates blood sugar over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34063-8
Short code
GH pre/p Gc SerPl-mCnc
Synonyms
GH pre/p Gc SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of diabetes, such as frequent urination, excessive thirst, or unexplained weight changes. It may also be recommended if you have other conditions like prediabetes, insulin resistance, or if you’re undergoing treatment for diabetes to monitor your progress.

What to Expect Before the Test

No special preparation is needed for this test. You may provide a blood sample (serum or plasma) during a routine clinic visit or lab draw. If you’re taking medications that affect blood sugar, let your provider know.

What the Test Measures

The test measures the concentration of glucose in your blood over 24 hours. Unlike a single blood glucose check, this profile gives a broader picture of how your body handles glucose throughout the day and night.

How the Test Results Are Used

Results help your healthcare provider determine if your diabetes is well-controlled, identify patterns in your blood sugar levels, or adjust treatments like medication or diet. Abnormally high or low readings may indicate issues like poor insulin function or other metabolic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glucose monitoring over 24 hours is particularly useful for diagnosing conditions like reactive hypoglycemia, where blood sugar drops too low after meals. It can also help detect subtle fluctuations that a single blood test might miss, aiding in personalized treatment plans for diabetes management.

Frequently asked questions

What does a 24-hour glucose profile tell me about my health?
It provides a detailed look at how your blood sugar levels change over time, helping identify patterns like spikes after meals, low points during sleep, or consistent high/low levels that may require medical attention.
How often should I get this test?
Your provider will determine the frequency based on your medical history, current treatments, and symptoms. Typically, it’s done once or twice a year for stable diabetes management, but more often if you’re adjusting treatments.
Can I eat or drink before the test?
No fasting is required for this test, but avoid sugary foods or drinks for at least 2 hours before your sample is taken to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy