Serum/plasma substance concentration for a specific protein marker (likely related to complement system)
This test measures the level of a protein involved in the immune system’s complement pathway, which helps protect the body from infections and inflammation.
["Understanding your complement protein levels can help identify immune system function or potential health concerns."]
Key facts at a glance
- LOINC
- 25529-9
- Short code
- GH SerPl-sCnc
- Synonyms
- GH SerPl-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects the concentration of a specific complement component in your blood, which plays a role in immune defense. This protein is part of a cascade that helps clear pathogens and regulate inflammation. While the exact protein may vary by lab, it is often linked to conditions affecting immune response or chronic inflammation.
Why It’s Done
Your healthcare provider may order this test if you have symptoms like frequent infections, autoimmune conditions, or signs of overactive inflammation. It can also help diagnose or monitor certain inherited or acquired immune disorders.
Common Reasons for Testing
Possible triggers include suspected immune deficiencies, unexplained infections, or conditions like lupus, vasculitis, or chronic inflammatory diseases. Some labs may also use it to screen for genetic complement disorders.
Sample Collection and Preparation
A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum or plasma, which is then sent to the lab for analysis. You may be asked to fast or avoid certain medications before the test, depending on the lab’s instructions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal levels of this complement protein can indicate immune system dysfunction. Low levels may suggest inherited deficiencies or chronic immune activation, while high levels could point to acute infections, inflammation, or certain autoimmune diseases. Early detection helps guide treatment decisions, such as immune-modulating therapies.
Short name
None
Frequently asked questions
What does a low level of this protein mean?
What does a high level indicate?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy