Serum/plasma mass concentration of aldosterone (measured via high-performance liquid chromatography)

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like high blood pressure, unusual thirst, frequent urination, or signs of fluid imbalance. It could also be used to diagnose conditions like primary aldosteroneism (Conn’s syndrome) or evaluate adrenal gland function.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into a vein (usually in your arm) to draw blood. If plasma is used, it may be collected from an arterial blood sample or processed from whole blood. Avoid caffeine or alcohol for 24 hours before testing if instructed.

What the Test Results Mean

Results are interpreted by your doctor based on your symptoms, medical history, and other test results. High aldosterone levels may indicate conditions affecting your adrenal glands or kidneys, while very low levels might suggest adrenal insufficiency or other hormonal imbalances.

Common Conditions Monitored or Diagnosed

This test helps diagnose or monitor conditions such as hyperaldosteronism (excess aldosterone), hypoaldosteronism (low aldosterone), or adrenal tumors. It may also be used in patients with hypertension, kidney disease, or those on certain medications that affect aldosterone levels.