Skip to content

Serum/plasma mass concentration of total protein

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood, which helps assess overall protein levels and kidney function.

Quick summary

["Total protein helps diagnose conditions like kidney disease or malnutrition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58848-3
Short code
GH sp16 SerPl-mCnc
Synonyms
GH sp16 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions affecting protein balance, such as kidney disease, liver problems, or malnutrition. It can also help monitor treatment responses in certain conditions.

What Does a High or Low Protein Level Mean?

High protein levels might indicate dehydration, liver disease, or certain cancers. Low protein levels could signal kidney disease, malnutrition, or severe infections.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then separated into serum or plasma for testing. This test does not require fasting.

Common Conditions Monitored

This test is often used to evaluate kidney function, detect liver disease, assess nutritional status, or screen for conditions like multiple myeloma or nephrotic syndrome.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule.
What are the typical reference ranges?
Reference ranges vary by lab and may include values such as 6.0 to 8.0 grams per deciliter (g/dL) for serum protein. Your specific range will be provided by your healthcare provider.
Can I eat or drink before this test?
No special preparation is needed for this test, including no restrictions on food or drink.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy