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Serum/plasma mass concentration of aldosterone (measured via mass spectrometry)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of aldosterone, a hormone produced by your adrenal glands that helps regulate blood pressure and fluid balance.

Quick summary

["Aldosterone helps control how much sodium and potassium your body retains, which can affect your blood pressure and heart function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27841-6
Short code
GH sp17 p chal SerPl-mCnc
Synonyms
GH sp17 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for conditions like primary aldosteroneism (also called Conn’s syndrome), adrenal gland tumors, or other hormonal imbalances that affect blood pressure or kidney function. It may also be used in patients with high blood pressure that doesn’t respond to usual treatments or those with symptoms like unexplained low potassium levels.

What Does a High or Low Level Mean?

High aldosterone levels may suggest conditions like primary aldosteroneism, where the adrenal glands produce too much aldosterone, leading to high blood pressure and low potassium. Low levels could indicate adrenal insufficiency or other issues affecting hormone production.

Sample Preparation and Testing Process

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is processed into serum or plasma and analyzed using advanced mass spectrometry to measure aldosterone concentration.

Common Conditions Monitored or Diagnosed

This test helps diagnose or monitor conditions such as hypertension (high blood pressure) resistant to treatment, hyperaldosteronism, adrenal adenomas, or other endocrine disorders. It may also be used to evaluate patients with symptoms like frequent urination, excessive thirst, or unexplained fatigue.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Aldosterone plays a critical role in regulating blood pressure and fluid balance. Abnormal levels can lead to serious health issues, including heart problems, kidney damage, or electrolyte imbalances. Early detection through this test can help manage these conditions more effectively.

Short name

Aldosterone Level (Serum/Plasma)

Frequently asked questions

What does an abnormal aldosterone level mean for my health?
An abnormal result may indicate an underlying hormonal imbalance or condition affecting your adrenal glands or blood pressure. Your doctor will discuss the results with you and may recommend further testing or treatments based on your symptoms and overall health.
How often will I need this test?
The frequency depends on your medical condition and treatment plan. Your doctor will determine how often you need this test based on your individual needs, such as whether you have a diagnosed condition like high blood pressure or adrenal issues.
Can I eat or drink anything before this test?
Typically, you may need to fast for a certain period before this test, but your doctor or lab will provide specific instructions. Avoiding certain foods, drinks, or medications may be necessary to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy