Serum/plasma mass concentration of aldosterone (measured via mass spectrometry)
This test measures the amount of aldosterone, a hormone produced by your adrenal glands that helps regulate blood pressure and fluid balance.
["Aldosterone helps control how much sodium and potassium your body retains, which can affect your blood pressure and heart function."]
Key facts at a glance
- LOINC
- 27841-6
- Short code
- GH sp17 p chal SerPl-mCnc
- Synonyms
- GH sp17 p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your doctor may order this test to check for conditions like primary aldosteroneism (also called Conn’s syndrome), adrenal gland tumors, or other hormonal imbalances that affect blood pressure or kidney function. It may also be used in patients with high blood pressure that doesn’t respond to usual treatments or those with symptoms like unexplained low potassium levels.
What Does a High or Low Level Mean?
High aldosterone levels may suggest conditions like primary aldosteroneism, where the adrenal glands produce too much aldosterone, leading to high blood pressure and low potassium. Low levels could indicate adrenal insufficiency or other issues affecting hormone production.
Sample Preparation and Testing Process
A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is processed into serum or plasma and analyzed using advanced mass spectrometry to measure aldosterone concentration.
Common Conditions Monitored or Diagnosed
This test helps diagnose or monitor conditions such as hypertension (high blood pressure) resistant to treatment, hyperaldosteronism, adrenal adenomas, or other endocrine disorders. It may also be used to evaluate patients with symptoms like frequent urination, excessive thirst, or unexplained fatigue.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Aldosterone plays a critical role in regulating blood pressure and fluid balance. Abnormal levels can lead to serious health issues, including heart problems, kidney damage, or electrolyte imbalances. Early detection through this test can help manage these conditions more effectively.
Short name
Aldosterone Level (Serum/Plasma)
Frequently asked questions
What does an abnormal aldosterone level mean for my health?
How often will I need this test?
Can I eat or drink anything before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy