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Serum/plasma mass concentration of protein using bromocresol green dye binding method

Published: August 9, 2026Updated: August 16, 2026

This test measures the total protein level in your blood, which includes both albumin and globulin proteins. Protein levels help assess overall health, kidney function, and nutritional status.

Quick summary

["Protein levels can indicate hydration, kidney health, or underlying conditions like liver disease or malnutrition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58847-5
Short code
GH sp17 SerPl-mCnc
Synonyms
GH sp17 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate your overall protein status, check for conditions affecting protein synthesis or loss (such as kidney disease, liver disease, or malnutrition), or monitor treatment responses in certain medical conditions.

What Does the Test Involve?

A blood sample is drawn from a vein, usually in your arm. The sample is processed to measure the total protein mass concentration using a specific dye-binding technique (bromocresol green). This method helps quantify the amount of protein in your serum or plasma.

What to Expect Before the Test

No special preparation is typically required, but you may be asked to fast for a few hours if instructed by your provider. Wear comfortable clothing and plan to rest for a short time after the draw.

What Are Common Causes of Abnormal Results?

Low protein levels may suggest conditions like severe kidney disease, liver failure, malnutrition, or excessive protein loss (e.g., from burns or chronic diarrhea). High protein levels could indicate dehydration, multiple myeloma, or certain inflammatory conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Total protein levels are a useful marker for assessing nutritional status, kidney function, and the body’s ability to retain proteins. Low protein levels can signal malnutrition or organ dysfunction, while persistently high levels may warrant further investigation into conditions like dehydration or certain cancers.

Short name

BCG Protein Mass Concentration

Frequently asked questions

How long does it take to get results?
Results are usually available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the findings with you during your follow-up visit.
What does a low protein level mean?
A low protein level may indicate poor nutrition, kidney problems, liver disease, or conditions causing excessive protein loss. Your provider will review your symptoms and other test results to determine the cause and next steps.
Can diet affect protein test results?
Diet can influence protein levels, especially if you have significant nutritional deficiencies. Avoiding high-protein foods for a few days before testing may not be necessary unless your provider specifies otherwise, as the test measures total protein mass rather than specific dietary intake.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy