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Serum/plasma mass concentration of protein (e.g., albumin or globulin)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which includes both albumin and other globulin proteins. Proteins are essential for maintaining fluid balance, supporting immune function, and transporting nutrients.

Quick summary

["Protein levels help assess hydration, liver function, and overall protein status in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58845-9
Short code
GH sp19 SerPl-mCnc
Synonyms
GH sp19 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like dehydration, liver disease, kidney problems, or malnutrition. It can also help monitor treatment responses, such as for certain cancers or chronic diseases.

What to Expect Before the Test

No special preparation is needed for this test. You may have a blood draw, where a small needle is used to collect a sample from your vein. If you’re on blood thinners, let your provider know before the test.

What Happens During the Test?

A healthcare professional will clean the area with an antiseptic, insert a small needle into your vein, and collect blood into a tube. The process usually takes a few minutes. You may feel a brief pinch, but it’s generally quick and painless.

What Are Possible Results?

Results are typically reported as a mass concentration (e.g., grams per deciliter). While reference ranges vary by lab, low levels may suggest protein loss (e.g., from kidney disease) or malnutrition, while high levels could indicate dehydration or conditions like multiple myeloma.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Level (Serum/Plasma)

Frequently asked questions

How long does it take to get my results?
Results are usually available within 1 to 3 business days, depending on your lab. Some labs may provide preliminary results sooner, but final interpretations require review by a healthcare professional.
Can I eat or drink before this test?
You can eat and drink normally before this test unless instructed otherwise. No fasting is required for protein level tests.
Will I experience any side effects from the blood draw?
Most people experience only minor discomfort or bruising at the injection site. Rarely, you might feel lightheaded or have a small lump. If you experience excessive pain or swelling, contact your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy