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Serum/plasma substance concentration for aldosterone (measured via immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of aldosterone, a hormone that helps regulate blood pressure and fluid balance in your body.

Quick summary

["Aldosterone helps control how much sodium and potassium your body retains, which affects blood pressure and fluid levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25776-6
Short code
GH sp1 p chal SerPl-sCnc
Synonyms
GH sp1 p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for conditions like primary aldosteroneism (Conn’s syndrome), adrenal insufficiency, or to monitor treatments for high blood pressure or kidney problems. It can also help diagnose conditions like hyperaldosteronism or adrenal tumors.

What Does a High or Low Level Mean?

High aldosterone levels may indicate overactive adrenal glands, which can lead to high blood pressure, kidney stones, or low potassium levels. Low levels might suggest adrenal gland problems or other hormonal imbalances.

Sample Preparation and Collection

This test requires a blood sample drawn from a vein in your arm. You may be asked to fast for a few hours before the test, depending on your doctor’s instructions. Avoid caffeine and certain medications for the recommended period.

What to Expect During the Test

The blood sample will be collected by a healthcare professional. You may feel a slight pinch, but it usually doesn’t cause discomfort. The sample is then sent to a lab for analysis using an immunoassay method.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Aldosterone plays a critical role in maintaining fluid and electrolyte balance. Abnormal levels can lead to serious health issues, including hypertension (high blood pressure), kidney disease, or electrolyte imbalances. Regular monitoring is important for patients with conditions affecting adrenal function or those on medications that influence aldosterone.

Short name

Aldosterone Level (Serum/Plasma)

Frequently asked questions

What causes abnormal aldosterone levels?
Abnormal aldosterone levels can be caused by conditions like primary aldosteronism (an overactive adrenal gland), adrenal tumors, kidney diseases, or certain medications. Stress, pregnancy, and some medications (like steroids) can also affect aldosterone levels.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your doctor will discuss the results with you during your follow-up visit.
Your doctor’s instructions will specify fasting requirements, but generally, you may drink water unless told otherwise. Avoid caffeine, alcohol, and certain medications for the recommended period before testing.
Follow your doctor’s instructions carefully. Wear comfortable clothing and plan to stay near the testing site for a short time. If you have any concerns or symptoms like dizziness or fainting, inform the healthcare provider before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy