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Serum or plasma mass concentration of growth hormone (GH) binding protein (GHBP)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a protein linked to growth hormone in your blood, which can help assess how your body responds to growth hormone.

Quick summary

["GHBP helps evaluate potential growth hormone deficiencies or resistance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50493-6
Short code
GH sp1 SerPl-mCnc
Synonyms
GH sp1 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Growth Hormone Binding Protein (GHBP)?

Growth hormone (GH) is a hormone produced by your pituitary gland that plays a key role in growth, metabolism, and cell repair. GHBP is a fragment of the GH receptor that remains in your blood after GH binds to it. Measuring GHBP can give doctors insight into how your body’s receptors are functioning, which may be important if you have suspected growth hormone issues.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like slow growth in children, muscle weakness, or metabolic problems in adults. It can also help monitor conditions like pituitary tumors or growth hormone deficiency.

How Is the Test Done?

A blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab for analysis. The test measures the mass concentration of GHBP in your serum or plasma.

What Do the Results Mean?

Results can vary based on individual health and medical history. Elevated levels might suggest certain receptor-related conditions, while lower levels could indicate potential hormone imbalance. Your doctor will interpret the results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: GHBP and Hormonal Balance

Short name

GH Binding Protein (GHBP)

Frequently asked questions

Why was this test ordered for me?
Your doctor may have ordered this test to check if your body’s growth hormone receptors are working properly, especially if you have symptoms like slow growth, muscle weakness, or metabolic concerns. It can also help diagnose or monitor conditions like pituitary disorders or growth hormone deficiency.
What does a high or low GHBP level mean?
A high GHBP level might suggest an overactive pituitary gland or other receptor-related issues, while a low level could indicate potential growth hormone deficiency or resistance. Your doctor will discuss these findings with you.
Do I need to prepare for this test?
No special preparation is needed, but avoid strenuous activity before the blood draw. Follow any specific instructions your doctor provides.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy