Skip to content

Serum or plasma mass concentration of aldosterone

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of aldosterone, a hormone produced by your adrenal glands that helps regulate blood pressure and fluid balance in your body.

Quick summary

["Aldosterone helps control how much sodium and potassium your body retains, which affects blood pressure and fluid levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27366-4
Short code
GH sp22 p chal SerPl-mCnc
Synonyms
GH sp22 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order an aldosterone test to diagnose or monitor conditions like primary aldosteroneism (also called Conn’s syndrome), adrenal insufficiency, or to check for hormonal imbalances that affect blood pressure or kidney function. It may also be used in conjunction with other tests to evaluate conditions like hypertension or mineralocorticoid excess.

What to Expect Before the Test

No special preparation is needed for this test. If your sample is drawn from blood, you may have a small needle inserted into your arm, and you might feel a brief pinch. If it’s a urine sample, you’ll collect a sample over 24 hours, but no special diet or restrictions apply.

What Happens During the Test?

Blood samples are typically taken from a vein in your arm and sent to a lab for analysis. The lab will measure the amount of aldosterone in your serum or plasma. If a urine sample is used, it’s collected over a full 24-hour period and analyzed for aldosterone excretion.

What Do the Results Mean?

Results are compared to reference ranges specific to your lab, which may vary. High aldosterone levels may indicate conditions like primary aldosteroneism, while low levels could suggest adrenal gland issues or other hormonal problems. Your doctor will interpret results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Aldosterone level

Frequently asked questions

What Causes High or Low Aldosterone Levels?
High aldosterone levels are often linked to conditions like primary aldosteroneism (where the adrenal glands overproduce aldosterone) or certain medications. Low aldosterone levels may result from adrenal gland disorders, such as Addison’s disease, or from conditions affecting hormone regulation.
How Does This Test Help Diagnose Conditions?
This test helps identify whether your symptoms—such as high blood pressure, frequent urination, or fatigue—are due to hormonal imbalances affecting aldosterone. It may also be used alongside other tests, like plasma renin activity, to confirm diagnoses like Conn’s syndrome or adrenal insufficiency.
Can This Test Be Done at Home?
No, aldosterone tests are typically performed in a clinical or laboratory setting. Blood or urine samples must be collected and processed by a healthcare professional to ensure accuracy.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy