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Serum/plasma mass concentration of aldosterone

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of aldosterone, a hormone produced by your adrenal glands that helps regulate blood pressure and fluid balance in your body.

Quick summary

["Aldosterone helps control how much salt and water your body retains, which can affect your blood pressure and kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27845-7
Short code
GH sp23 p chal SerPl-mCnc
Synonyms
GH sp23 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for conditions like primary aldosteroneism (also called Conn’s syndrome), adrenal gland tumors, or other hormonal imbalances that affect blood pressure or kidney function. It may also be used to monitor treatment for conditions such as hypertension or adrenal disorders.

What Does a High or Low Level Mean?

High aldosterone levels may indicate conditions like primary hyperaldosteronism, which can cause high blood pressure, low potassium levels, or kidney problems. Low levels might suggest adrenal insufficiency or other hormonal issues that need further evaluation.

Sample Collection and Preparation

This test requires a blood sample drawn from a vein in your arm. The blood is collected in a special tube and sent to a lab for analysis. Plasma or serum is used, depending on the lab’s standard procedure.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to avoid certain medications (like some blood pressure drugs) or foods (like salt) for a short time before testing, depending on your doctor’s instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Aldosterone Level

Frequently asked questions

What causes abnormal aldosterone levels?
Abnormal aldosterone levels can result from conditions like adrenal tumors, kidney disease, certain medications (e.g., steroids, some blood pressure drugs), or genetic disorders. Primary hyperaldosteronism (too much aldosterone) often causes high blood pressure and low potassium, while low levels may signal adrenal insufficiency or other hormonal imbalances.
How is aldosterone tested?
A blood sample is taken, and the lab measures the amount of aldosterone in the plasma or serum using a sensitive analytical method, such as mass spectrometry or immunoassay. The test is typically done in a clinical laboratory setting.
Can diet or medications affect aldosterone levels?
Yes, certain foods (like high-sodium diets) and medications (such as diuretics, steroids, or blood pressure medications) can influence aldosterone levels. Your doctor may recommend dietary or medication adjustments before testing to get more accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy