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Serum or plasma mass concentration of protein (e.g., albumin, globulin, or other proteins)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, often used to assess overall protein levels or specific protein types like albumin or globulins.

Quick summary

["Protein levels in your blood can help diagnose or monitor conditions like kidney disease, liver issues, or nutritional deficiencies."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58842-6
Short code
GH sp25 SerPl-mCnc
Synonyms
GH sp25 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions affecting protein production, breakdown, or retention in your body. It can also help evaluate kidney function, liver health, or responses to treatments like dialysis or certain medications.

What Does a Result Mean?

Results may indicate normal protein levels, low protein (hypoproteinemia), or high protein (hyperproteinemia). Low levels might suggest conditions like malnutrition, kidney disease, or liver problems, while high levels could be seen in dehydration, multiple myeloma, or certain infections.

Common Conditions Monitored

This test is often used to monitor protein-related conditions, such as chronic kidney disease, liver cirrhosis, or inflammatory diseases. It may also be part of routine blood work to assess overall health.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma for testing. You may be asked to fast before the test, depending on the specific protein being measured.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

What Are My Next Steps If My Results Are Abnormal?
If your results show abnormal protein levels, your healthcare provider will discuss further testing or treatments tailored to your condition. They may recommend additional blood tests, imaging, or lifestyle changes to address the underlying issue.
How Often Should I Get This Test?
The frequency depends on your health condition and treatment plan. Your provider will determine how often to repeat this test based on your medical needs, such as monitoring chronic diseases or responding to treatments.
Can I Prepare for This Test at Home?
Yes, follow your provider’s instructions for fasting or other preparations if required. Avoid smoking or consuming certain foods/drinks before the test to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy