Serum or Plasma Substance Concentration of Aldosterone (Mass Concentration)

Why Is This Test Done?

Your doctor may order this test to diagnose or monitor conditions such as primary or secondary hyperaldosteronism, adrenal insufficiency, or certain types of high blood pressure (e.g., resistant hypertension). It can also help evaluate kidney function or rule out conditions like Conn’s syndrome.

What to Expect Before the Test

No special preparation is needed, but you may be asked to avoid certain medications (like potassium-sparing diuretics) for a few days before testing. If you’re on blood pressure medications, check with your doctor first. Blood is drawn from a vein, usually in your arm.

What Happens During the Test?

A healthcare provider will clean the area where the needle will go, insert a small needle into your vein, and collect a blood sample. You may feel a slight pinch, but it usually doesn’t cause discomfort. The sample is then sent to a lab for analysis.

What Are the Possible Results?

Results are compared to standard reference ranges, but exact values can vary by lab. High aldosterone levels may indicate overactivity of your adrenal glands, while low levels could suggest adrenal gland problems or other health issues.