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Serum or plasma mass concentration of serum protein (general protein measurement)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum or plasma, which helps assess overall protein levels in your body.

Quick summary

["Protein levels can indicate hydration status, kidney function, or other health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58877-2
Short code
GH sp30 SerPl-mCnc
Synonyms
GH sp30 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if they suspect conditions like dehydration, kidney disease, liver problems, or certain infections. It can also be used to monitor long-term health or after treatments that affect protein balance.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw if your provider specifies. Wear comfortable clothing and plan to rest for a short time afterward.

What the Test Involves

A healthcare professional will draw blood from a vein, typically in your arm. The blood sample is then sent to a lab for analysis. The test is quick and generally painless, though you might feel a slight pinch during the procedure.

What the Results Mean

Results are compared to standard reference ranges for protein concentration in blood. Abnormally low levels may suggest dehydration, malnutrition, or kidney issues, while very high levels could indicate conditions like multiple myeloma or severe liver disease.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time.
What causes protein levels to be too low?
Protein levels may be low due to conditions like kidney disease, liver problems, malnutrition, severe infections, or certain medications. Chronic conditions or rapid weight loss can also contribute.
Can I eat or drink before this test?
Most of the time, no special diet is required, but always follow your healthcare provider’s instructions. If fasting is required, avoid food and liquids (except water) for the specified period before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy