Serum/Plasma Mass Concentration of Serum Protein (General Protein Measurement)
This test measures the total amount of protein in your blood, which helps assess overall protein levels in serum or plasma.
["Protein levels in your blood can give important clues about your health."]
Key facts at a glance
- LOINC
- 58876-4
- Short code
- GH sp31 SerPl-mCnc
- Synonyms
- GH sp31 SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Doctors may order this test to evaluate conditions affecting protein synthesis, breakdown, or kidney function. It can also help diagnose or monitor diseases like liver disease, malnutrition, or kidney problems. Sometimes, it’s used to check for protein-losing conditions, such as certain types of heart or lung disease.
What to Expect Before the Test
No special preparation is usually needed. You may be asked to fast for a few hours before the test if it’s part of a more complex evaluation, but this is not always the case. Your blood will be drawn from a vein, typically in your arm, and you may feel a brief pinch or slight discomfort.
What the Test Results Mean
Results are compared to standard ranges for healthy adults. Low protein levels may indicate malnutrition, liver or kidney disease, or excessive protein loss. High levels could suggest dehydration, inflammation, or certain medical conditions. Your doctor will interpret the results in the context of your overall health and symptoms.
Common Conditions Monitored
This test is often used to monitor conditions like chronic kidney disease, liver cirrhosis, severe infections, or inflammatory diseases. It may also be part of routine check-ups for people with known protein-related disorders.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
What causes low protein levels in blood?
What causes high protein levels in blood?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy