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Serum or plasma mass concentration of total protein (including albumin and globulins)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which includes important substances like albumin and other globulins. Proteins help with blood clotting, immune function, and maintaining fluid balance in your body.

Quick summary

["Your blood protein levels can indicate overall health, hydration status, and potential medical conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
59043-0
Short code
GH sp34 SerPl-mCnc
Synonyms
GH sp34 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to check for conditions like dehydration, liver disease, kidney problems, or malnutrition. It can also help monitor treatment responses in certain illnesses.

What to Expect Before the Test

No special preparation is usually needed. You may fast before the test if instructed by your healthcare provider, but this depends on the clinic’s protocol. Bring any medications you’re currently taking.

What Happens During the Test?

A healthcare professional will draw blood from a vein, typically in your arm. The process takes a few minutes, and you may feel a brief pinch. The blood sample is then sent to a lab for analysis.

What Are Possible Results?

Results are typically reported in grams per deciliter (g/dL). Abnormally high or low levels may signal underlying health concerns that require further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein Level

Frequently asked questions

What Does It Mean If My Results Are Abnormal?
High protein levels might suggest dehydration, multiple myeloma, or severe infections. Low protein levels could indicate liver disease, kidney problems, or malnutrition. Always discuss results with your doctor for personalized interpretation.
How Often Should I Get This Test?
Your doctor will determine the frequency based on your health status, symptoms, or ongoing treatment. Regular monitoring may be needed if you have chronic conditions like kidney or liver disease.
Can I Eat or Drink Before the Test?
Follow your doctor’s instructions, but generally, you can eat and drink normally unless specified otherwise. Some labs may ask for fasting, so check with them beforehand.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy