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Serum or Plasma Total Protein by Bromocresol Green (BCG) Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which includes both albumin and globulin proteins. Protein is essential for maintaining fluid balance, supporting immune function, and transporting nutrients.

Quick summary

["Total protein levels help assess hydration, liver function, and overall protein synthesis in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58868-1
Short code
GH sp40 SerPl-mCnc
Synonyms
GH sp40 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions affecting protein production, such as liver disease, kidney problems, or malnutrition. It can also help diagnose or monitor conditions like edema (fluid retention), malnutrition, or certain immune disorders.

What Does a Result Mean?

Results may be used to compare against general reference ranges to identify potential imbalances. For example, low protein levels might suggest liver disease or malabsorption, while very high levels could indicate dehydration or multiple myeloma.

Common Conditions Affecting Protein Levels

Conditions like chronic liver disease, kidney failure, or severe infections can alter protein levels. Certain medications or dietary factors may also influence these measurements.

What Preparations Are Needed?

No special preparation is typically required, but you may be asked to fast for a few hours before the test if instructed by your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Total protein levels are clinically significant because they reflect overall protein status in the body. Abnormalities can indicate underlying health issues requiring further evaluation, such as nutritional deficiencies or organ dysfunction.

Short name

Total Protein

Frequently asked questions

How long does it take to get my results?
Results are usually available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
Unless instructed otherwise, you can eat and drink normally before this test. Some tests may require fasting, but this test does not. Always follow your provider’s specific instructions.
What if my protein levels are outside the normal range?
If your results are outside the expected range, your healthcare provider will review them with you and may recommend additional tests or treatments to address potential causes, such as dietary changes, medication adjustments, or further medical evaluation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy