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Serum or Plasma Substance Concentration for a Specific Protein (Bromocresol Green Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the concentration of a specific protein in your blood using a dye-binding method. It may be used to assess protein levels related to liver function, kidney health, or other conditions.

Quick summary

["This test helps doctors check protein levels in your blood that could indicate health issues like liver disease or kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12687-0
Short code
GH sp4 p chal SerPl-sCnc
Synonyms
GH sp4 p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence and amount of a particular protein in your blood. Bromocresol green, a dye, binds to proteins, and the test measures how much dye is bound to determine protein concentration. This method is often used for general protein screening or specific protein monitoring.

Why It Might Be Ordered

Your healthcare provider may order this test if they suspect liver disease, kidney dysfunction, or other conditions affecting protein metabolism. It can also be part of routine monitoring for patients with chronic illnesses.

Sample Collection and Preparation

Blood is drawn from a vein, typically in your arm. The sample is collected in a tube that separates serum (liquid part) or plasma (blood without clotting factors) for testing. This test can be performed on either serum or plasma.

Preparation for the Test

No special preparation is needed for this test. You may continue with your normal activities, but avoid heavy meals or excessive alcohol before the blood draw if instructed by your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Changes in protein levels detected by this test can signal underlying health conditions. For example, elevated levels might indicate liver disease, while low levels could suggest kidney problems or malnutrition. This test is often used as a screening tool or to monitor existing conditions.

Short name

BCG Protein Assay (Serum/Plasma)

Frequently asked questions

What does a high or low result mean?
A high result may suggest conditions like liver disease or protein-losing syndromes, while low results could indicate kidney disease, malnutrition, or other metabolic issues. Your doctor will interpret results in the context of your overall health and symptoms.
How often should I get this test?
The frequency depends on your health condition and medical needs. Your doctor will determine how often you need this test based on your diagnosis, treatment plan, and symptoms.
Can I eat or drink before this test?
Typically, you can eat and drink normally unless your doctor advises otherwise. Avoid heavy meals or excessive alcohol before the blood draw if specified by your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy