Serum or plasma substance concentration of a specific protein marker (likely related to serum amyloid P component, SAP)
This test measures the level of a protein called serum amyloid P, which is often associated with chronic inflammation or amyloid deposits in the body. It may be used in certain conditions where these factors are suspected.
["This test helps assess chronic inflammation or amyloid-related conditions, though results alone may not diagnose specific diseases."]
Key facts at a glance
- LOINC
- 12688-8
- Short code
- GH sp5 p chal SerPl-sCnc
- Synonyms
- GH sp5 p chal SerPl-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you have symptoms or risk factors for conditions like chronic inflammation, amyloidosis, or other systemic diseases. It can also be part of monitoring for certain chronic illnesses.
What Does the Test Measure?
Serum amyloid P (SAP) is a protein found in high concentrations during chronic inflammation. Elevated levels may indicate ongoing inflammation or amyloid deposits in organs, though SAP itself is not the primary amyloid protein (that is typically measured separately).
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The sample is then processed to separate serum or plasma for testing. The test measures the concentration of SAP using a specialized immunoassay or similar method.
What Are Possible Results?
Results are reported as a concentration value (e.g., milligrams per deciliter). While elevated SAP can suggest inflammation or amyloid involvement, it is not a definitive test for amyloidosis or other diseases. Interpretation depends on clinical context.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Serum Amyloid P (SAP) concentration
Frequently asked questions
What does an elevated SAP level mean?
What does a normal SAP level mean?
Can SAP levels change over time?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy