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Serum/plasma substance concentration by immunoassay (tetramethylbenzidine signal) for a specific protein linked to serum albumin-related conditions

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein associated with albumin function in your blood, often used to assess kidney or liver health.

Quick summary

["Helps evaluate conditions affecting protein balance in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12689-6
Short code
GH sp6 p chal SerPl-sCnc
Synonyms
GH sp6 p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like swelling, fatigue, or changes in urine output that could indicate kidney or liver problems. It may also be used to monitor certain chronic conditions or after treatments affecting protein levels.

What to Expect Before the Test

No special preparation is needed, but avoid alcohol for 24 hours before testing. Fasted or non-fasted states may not affect results, but follow your provider’s instructions.

How the Test Works

A blood sample is drawn from a vein, typically in your arm. The sample is processed to measure the concentration of a protein linked to albumin function using a sensitive immunoassay method.

What the Results Mean

Results help determine if your body is producing or retaining proteins normally. Abnormal levels may signal conditions like kidney disease, liver dysfunction, or malnutrition.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test may detect subtle protein abnormalities that aren’t captured by standard albumin measurements, aiding in early diagnosis of systemic conditions affecting protein metabolism.

Short name

Albumin-related protein measurement (CLIA-based)

Frequently asked questions

Will I need to fast before this test?
No fasting is required, but avoid alcohol for 24 hours to reduce potential interference. Follow your provider’s specific instructions if they recommend fasting for other reasons.
What does a low or high result indicate?
Low levels may suggest kidney issues, liver disease, or malnutrition. High levels could indicate dehydration or certain genetic conditions. Your provider will interpret results in context with your symptoms and medical history.
How often will I need this test?
Frequency depends on your health status. Your provider may order it periodically to monitor chronic conditions, during treatment adjustments, or if symptoms recur.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy