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Serum/plasma substance concentration for a specific protein marker (likely related to serum amyloid P component)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of serum amyloid P protein, a protein found in blood that can help assess conditions involving inflammation or amyloid deposits.

Quick summary

["Helps evaluate inflammation or amyloid-related diseases with blood tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12691-2
Short code
GH sp8 p chal SerPl-sCnc
Synonyms
GH sp8 p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Serum Amyloid P Used For?

Serum amyloid P (SAP) is primarily used to monitor conditions where abnormal protein deposits, such as amyloid, may be present. It can also be part of broader inflammatory assessments, though it’s not as commonly ordered alone as other markers like CRP (C-reactive protein).

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is then processed to separate serum or plasma, where the SAP protein level is measured using a specialized immunoassay or similar method. Results are reported as a concentration value in standard units (e.g., mg/dL).

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms or risk factors for conditions like amyloidosis (a disease where abnormal proteins build up in organs) or chronic inflammatory diseases. It may also be used in research or specialized diagnostic protocols for conditions like systemic lupus erythematosus or other connective tissue disorders.

What Do Results Mean?

Elevated SAP levels can indicate inflammation or amyloid deposition, but it’s not a definitive test for amyloidosis alone. Results are interpreted alongside clinical findings, other tests, and patient history to guide diagnosis or management.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Amyloid P (SAP) Concentration

Frequently asked questions

Why do I need to know my SAP level?
Your SAP level helps assess whether inflammation or amyloid-related issues are present, but it’s often part of a broader diagnostic approach. Elevated levels may prompt further testing or evaluation for conditions like amyloidosis or chronic inflammatory diseases. Always discuss results with your healthcare provider for personalized insights.
How long will it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times and your healthcare provider’s workflow. Your provider will contact you once results are ready.
Can I eat or drink before this test?
You can usually eat and drink normally before this test unless instructed otherwise by your provider. Blood tests like this are generally not affected by food or drink, but follow any specific fasting instructions if provided.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy