Skip to content

Serum or plasma concentration of **digoxin** (digitalis glycoside)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of digoxin, a medication used to treat certain heart conditions, in your blood. It helps ensure you’re receiving the right dose.

Quick summary

["Digoxin levels help balance heart rhythm and prevent overdosage."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24151-3
Short code
Giant Ragweed IgG Qn
Synonyms
Giant Ragweed IgG Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order a digoxin test if you’re taking digoxin (brand names like Lanoxin) to treat conditions like heart failure, atrial fibrillation, or irregular heartbeats. It’s also used to monitor levels in people with kidney problems, as these organs help clear the drug from your body. Sometimes, it’s checked before surgery or if you experience symptoms like nausea, vomiting, or vision changes that might signal too much or too little of the medication.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for a few hours before the blood draw if your test involves serum. Bring a list of all medications, including over-the-counter drugs and supplements, to share with your healthcare provider. Avoid smoking or drinking coffee for 30 minutes before the test if instructed.

What Happens During the Test

A healthcare professional will insert a small needle into a vein in your arm to draw blood. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood sample is then sent to a lab for analysis. The test typically takes a few minutes, and you can return to your normal activities afterward.

What the Results Mean

Results are usually reported as a concentration in nanograms per milliliter (ng/mL). Too much digoxin can cause symptoms like dizziness, headaches, or irregular heartbeat, while too little may not provide enough heart support. Your doctor will interpret the results in relation to your symptoms, other medications, and kidney function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Digoxin Level

Frequently asked questions

How often should I get this test?
Your doctor will determine the frequency based on your medical condition, how long you’ve been taking digoxin, and whether you have kidney problems. Typically, tests are done every few weeks or months to check for stable levels, but this can vary. Always follow your healthcare provider’s schedule.
What happens if my digoxin level is too high?
If your digoxin level is too high, your doctor may adjust your dose, prescribe a medication to help clear the drug from your body, or monitor you closely. Symptoms of toxicity include nausea, vomiting, vision changes, or irregular heartbeat. Seek medical attention immediately if you experience these signs.
Most of the time, you can eat and drink normally unless your doctor specifies otherwise. If fasting is required, follow their instructions carefully. For example, some labs may ask you to avoid food for 8–12 hours before drawing serum samples.
Yes, digoxin levels directly influence your medication dose. Your doctor will adjust your prescription based on the results to avoid toxicity or insufficient treatment. They may also consider other factors like kidney function, heart condition severity, and other medications you’re taking.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy