Multigene Mutation Panel for Tissue Samples (Genetic Testing)
This test checks for specific genetic mutations across multiple genes in a tissue sample, helping identify potential inherited conditions or cancer risks.
["A genetic test to detect mutations in multiple genes from your tissue sample."]
Key facts at a glance
- LOINC
- 102117-9
- Short code
- GIST multigene mut pnl Tiss
- Synonyms
- GIST multigene mut pnl Tiss
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
This test measures specific substances, cells, or markers in your body to help your healthcare provider understand how well certain organs and systems are working and whether there are any signs of illness that need further attention.
The test analyzes DNA sequences from your tissue to identify variations (mutations) in genes associated with inherited disorders, cancer susceptibility, or other genetic conditions. Results may indicate whether certain genetic traits or predispositions are present.
During the test, a small sample is collected from you and analyzed using standard laboratory methods. The equipment measures the levels or characteristics of what is being tested, and the findings are reported as values your provider can interpret and explain.
A small sample of tissue (e.g., blood, saliva, or biopsy) is collected and processed to extract DNA. Advanced laboratory techniques (such as next-generation sequencing) compare your DNA against known genetic references to detect mutations across multiple genes.
Your provider may order this test to help diagnose a medical condition, monitor a disease you already have, check how well a current treatment is working, or screen for potential problems before symptoms appear.
Your healthcare provider may recommend this test if you have a family history of genetic disorders, symptoms of a suspected genetic condition, or if you’re at higher risk for certain cancers or other inherited diseases.
Before the test, your provider will give you specific instructions, which may include fasting for a certain number of hours, avoiding certain medications or supplements, or drinking extra water. Tell your care team about all medications you take and ask any questions ahead of time.
No special preparation is usually needed unless your provider specifies otherwise. If a tissue sample (e.g., biopsy) is required, follow their instructions for collection and handling. You may need to discuss your medical history and family health with your provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Genetic Mutation Screening
Frequently asked questions
Identifying specific genetic mutations can help guide treatment options, monitor disease progression, or inform preventive strategies. For example, mutations in certain genes may link to conditions like breast cancer, heart disease, or neurological disorders.
Results may take several weeks to months, depending on the complexity of the test and laboratory processing. Your provider will contact you once results are available, and they’ll explain what they mean for your health.
Yes, you have the right to refuse this test. Always discuss your concerns with your healthcare provider before proceeding.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy