Gluten IgA Antibodies (Total) with Anti-endomysial Antibody Confirmation
This test measures your body’s immune response to gluten, a protein found in wheat, barley, and rye, which may indicate celiac disease or gluten sensitivity.
["Helps diagnose conditions linked to gluten exposure and guides dietary decisions."]
Key facts at a glance
- LOINC
- 16900-3
- Short code
- Gliadin Ab Sal-aCnc
- Synonyms
- Gliadin Ab Sal-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test includes two key components: total IgA antibodies against gluten (gluten-specific) and confirmation with anti-endomysial antibodies. These markers help identify an immune reaction to gluten, which can trigger inflammation in the small intestine in celiac disease.
Why It Matters for Your Health
If your body produces these antibodies, it may signal an immune response to gluten, potentially causing damage to the small intestine (celiac disease) or other gastrointestinal symptoms. This test is crucial for diagnosing celiac disease or gluten-related disorders.
How the Test Works
Blood is drawn to detect IgA antibodies against gluten and anti-endomysial antibodies. The presence of these antibodies suggests an immune-mediated reaction to gluten, which can be confirmed with further testing if needed.
Common Symptoms to Watch For
If you have symptoms like persistent diarrhea, abdominal pain, weight loss, fatigue, or unexplained nutrient deficiencies, this test may be recommended to check for gluten-related conditions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results for gluten-specific IgA antibodies combined with anti-endomysial antibodies strongly suggest celiac disease. These antibodies indicate an abnormal immune response to gluten, which can damage the small intestine lining over time. Early diagnosis allows for dietary changes to prevent long-term complications.
Short name
Gluten-related antibody panel
Frequently asked questions
What does a positive result mean?
Can this test be done without fasting?
What if my test results are negative but I still have symptoms?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy