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Gluten Immunoglobulin G (IgG) Antibody Serum Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of antibodies your body produces in response to gluten, a protein found in wheat, barley, and rye. It helps identify potential celiac disease or gluten sensitivity.

Quick summary

["This test checks for gluten-related immune reactions in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7893-1
Short code
Gliadin Ab Ser-aCnc
Synonyms
Gliadin Ab Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies specific to gliadin, a fraction of gluten. These antibodies are part of your immune system’s response when your body reacts to gluten, which can occur in conditions like celiac disease or non-celiac gluten sensitivity.

Why Might You Need This Test?

Your doctor may recommend this test if you have symptoms like digestive issues (e.g., bloating, diarrhea), fatigue, or unexplained weight loss, especially after consuming gluten-containing foods. It can also be used as part of a diagnostic workup for celiac disease or gluten-related disorders.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The sample is then analyzed in a lab to measure the concentration of gluten-specific IgG antibodies. The result helps determine if your immune system is reacting to gluten.

What Do the Results Mean?

Results are not provided with specific numeric ranges. Instead, they are interpreted by your healthcare provider based on your symptoms, medical history, and other test results. High levels may suggest an immune response to gluten, while low or normal levels may indicate no significant reaction.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Anti-Gluten Antibody

Frequently asked questions

What are the typical symptoms that might lead to this test?
Symptoms like persistent digestive issues (e.g., stomach pain, bloating, diarrhea), unexplained weight loss, fatigue, or other non-specific symptoms (e.g., anemia, skin rashes) after consuming gluten-containing foods could prompt this test.
How long does it take to get the results of this test?
Test results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your doctor will discuss the results with you during a follow-up visit.
Can I eat gluten before the test?
Yes, you can eat a normal gluten-containing diet before the test. This test measures your natural immune response to gluten, so it does not require a special diet beforehand.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy