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Gluten IgA Antibodies (Total) with Tissue Transglutaminase IgA Antibodies (TGA) - Serum

Published: August 9, 2026Updated: August 16, 2026

This blood test measures antibodies your body makes in response to gluten, a protein found in wheat, barley, and rye. It helps identify celiac disease or gluten sensitivity.

Quick summary

["This test helps diagnose conditions linked to gluten exposure and may guide dietary changes or medical treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109389-7
Short code
Gliadin IgA Msmt Ser
Synonyms
Gliadin IgA Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Gluten sensitivity or celiac disease can cause digestive issues, fatigue, or other symptoms. This test checks for specific antibodies that signal your immune system’s reaction to gluten, even if you don’t have obvious symptoms.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before your blood draw. Wear a loose shirt for easy access.

What the Results Mean

High levels of these antibodies often mean your immune system is reacting to gluten, which can damage the small intestine in celiac disease. Your doctor will interpret results in the context of your symptoms and medical history.

Common Symptoms to Watch For

If you have symptoms like chronic diarrhea, bloating, weight loss, or fatigue, this test may be recommended. Some people with celiac disease don’t have symptoms but still need testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results strongly suggest celiac disease or gluten sensitivity. They help confirm a diagnosis, monitor treatment progress, or rule out other conditions. Always discuss results with your healthcare provider.

Short name

Gluten-related antibody panel

Frequently asked questions

What triggers this test?
Your doctor may order this test if you have symptoms like digestive issues, unexplained fatigue, or a family history of celiac disease. It’s also used to screen people with autoimmune disorders or unexplained nutrient deficiencies.
How are results interpreted?
Results are compared to reference ranges for your age and health. Elevated antibody levels often indicate an immune response to gluten, but further testing (like an endoscopy) may be needed to confirm intestinal damage.
Can I eat gluten before the test?
Yes, you can eat your usual diet before testing. However, if you’re suspected of celiac disease, your doctor may ask you to follow a gluten-free diet for 4–6 weeks before testing to avoid false negatives.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy