Gluten IgA Antibody (Total) – Serum
This test measures the level of Immunoglobulin A (IgA) antibodies produced in response to gluten, a protein found in wheat, barley, and rye. It helps detect celiac disease or gluten sensitivity.
["This test checks for gluten-related immune reactions in your blood."]
Key facts at a glance
- LOINC
- 96283-7
- Short code
- Gliadin IgE Qn
- Synonyms
- Gliadin IgE Qn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you have symptoms like stomach pain, diarrhea, fatigue, or unexplained weight loss. It’s also used to screen for celiac disease, a condition where gluten triggers an immune response that damages the small intestine. Sometimes, doctors check IgA antibodies first before testing for other gluten-related antibodies, like IgG or tTG (tissue transglutaminase).
What Does a Positive Result Mean?
A positive result means your body is producing IgA antibodies against gluten. This can indicate celiac disease or another gluten-related condition. However, a positive test alone doesn’t confirm the diagnosis—your doctor will likely follow up with additional tests, like endoscopy or genetic screening, to make a full assessment.
What to Expect Before the Test
No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. If you’re on blood thinners or have a history of bleeding, let your doctor know beforehand.
What to Expect After the Test
After the blood is drawn, you can return to your normal activities. You might feel slight discomfort at the injection site, but it should go away quickly. If you experience excessive bruising, swelling, or pain, contact your doctor.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Gluten IgA Antibodies
Frequently asked questions
This test is primarily used as part of the diagnostic process for celiac disease or gluten sensitivity. Low IgA levels can sometimes interfere with antibody testing, so doctors may check IgA first to rule out this issue before proceeding with other tests. A normal IgA level doesn’t rule out celiac disease, so additional testing (like tTG-IgA or endoscopy) may still be needed.
What if I Have a Low IgA Level?
Does This Test Differentiate Between IgA and IgG Antibodies?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy