Gluten IgA Antibody (Anti-Gliadin) Total Immunoassay
This test measures the level of antibodies your body produces in response to gluten, a protein found in wheat, barley, and rye. It helps identify potential gluten sensitivity or celiac disease.
["Helps detect gluten-related conditions by checking for immune system reactions to gluten."]
Key facts at a glance
- LOINC
- 63261-2
- Short code
- Gliadin IgG Titr CSF IA
- Synonyms
- Gliadin IgG Titr CSF IA
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 8
- Ref high
- 61
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 82977
- SNOMED
- 3110003
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like persistent diarrhea, weight loss, fatigue, or abdominal pain. It may also be used as part of a broader evaluation for gluten-related disorders, especially if you suspect celiac disease or non-celiac gluten sensitivity. Sometimes, it’s ordered alongside other tests like total IgA levels to ensure accurate results.
What to Expect Before the Test
No special preparation is needed for this blood test. You can eat and drink normally on the day of your visit. If you’re taking medications, let your healthcare provider know, as some may affect test results.
What Happens During the Test
A healthcare professional will draw blood from a vein in your arm. The process is quick and typically causes only mild discomfort. The blood sample is then sent to a lab for analysis using an immunoassay method to detect gluten-specific antibodies.
What the Results Mean
Results are qualitative (positive or negative) and indicate whether your body has produced antibodies against gluten. A positive result suggests an immune response, which may warrant further testing or evaluation by a specialist.
Reference range
Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated levels of gluten-specific IgA antibodies can signal gluten sensitivity or celiac disease. However, false positives can occur, so additional testing (like endoscopy or genetic testing for HLA-DQ2/DQ8) may be needed to confirm a diagnosis. This test is not definitive on its own but is a useful first step in identifying potential gluten-related issues.
Short name
Gluten IgA Antibody
Frequently asked questions
Can this test diagnose celiac disease?
What if my IgA levels are low?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy