Serum IgA Anti-Gliadin Antibodies (Immunoassay)
This test measures the presence of antibodies against gliadin, a protein found in gluten, in your blood. It may help evaluate potential gluten sensitivity or celiac disease.
["This test helps identify possible gluten-related digestive issues."]
Key facts at a glance
- LOINC
- 57776-7
- Short code
- Gliadin peptide IgA & IgG pnl Ser
- Synonyms
- Gliadin peptide IgA & IgG pnl Ser
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like persistent diarrhea, abdominal pain, weight loss, or fatigue, especially if you’ve been diagnosed with or suspect gluten sensitivity or celiac disease. It may also be used as part of a broader evaluation for autoimmune conditions linked to gluten exposure.
What to Expect Before the Test
No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, and you can eat and drink as usual. If you’re on certain medications or have a history of bleeding disorders, let your provider know beforehand.
What the Results Mean
High levels of these antibodies may suggest gluten sensitivity or celiac disease, but they are not definitive. Your provider will consider your symptoms, medical history, and possibly additional tests to make a diagnosis. False positives can occur, so results should be interpreted in the context of your overall health.
Common Symptoms Linked to This Test
Gluten sensitivity or celiac disease can cause symptoms such as bloating, stomach cramps, nausea, or long-term issues like nutrient deficiencies if untreated. If you experience these symptoms after eating gluten-containing foods, discuss them with your doctor.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
IgA anti-gliadin antibodies are often measured as part of an initial screening for celiac disease or gluten-related disorders. While they can indicate exposure to gluten, they are not always diagnostic on their own. Positive results may prompt further testing, such as a gluten challenge or tissue biopsy, to confirm a diagnosis. They can also appear in people without celiac disease but who have gluten sensitivity or other autoimmune conditions.
Short name
IgA Anti-Gliadin Antibody Test
Frequently asked questions
What does a positive result mean?
Can this test be done at home?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy