Serum IgA Anti-Gliadin Antibodies (Peptide-Specific)
This test measures antibodies in your blood that target gliadin, a protein found in gluten. It helps assess possible gluten sensitivity or celiac disease.
["This test checks for gluten-related immune responses that may signal digestive or health concerns."]
Key facts at a glance
- LOINC
- 101564-3
- Short code
- Gliadin peptide IgA+IgG Ser IA-aCnc
- Synonyms
- Gliadin peptide IgA+IgG Ser IA-aCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your doctor may recommend this test if you have symptoms like persistent stomach pain, bloating, diarrhea, or unexplained weight loss. It’s also used when screening for celiac disease or gluten sensitivity, especially if other tests or symptoms suggest gluten exposure.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. If you’re on a gluten-free diet, your doctor may advise temporarily reintroducing gluten to see if symptoms return.
What the Results Mean
High levels of these antibodies may indicate an immune reaction to gluten, supporting a diagnosis of gluten sensitivity or celiac disease. However, they’re not definitive on their own and may be used alongside other tests.
Common Symptoms Linked to Positive Results
Positive results often correlate with symptoms like abdominal discomfort, nutrient deficiencies (e.g., iron or vitamin D), or long-term digestive issues. Some people may also experience fatigue or skin rashes.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
These antibodies are markers of gluten-related immune responses. While they don’t diagnose celiac disease directly, they’re useful for identifying potential gluten sensitivity. Elevated levels may prompt further testing, such as a gluten challenge or endoscopy, to confirm a diagnosis and guide dietary or medical management.
Short name
IgA Anti-Gliadin Antibody Test
Frequently asked questions
What does a positive result mean?
Can I eat gluten before this test?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy