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Gluten-Dependent IgA Anti-Gliadin Peptide Antibody (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies (IgA) to gluten-derived peptides in your blood, which may indicate a sensitivity to gluten in celiac disease or non-celiac gluten sensitivity.

Quick summary

["This test helps identify potential gluten-related immune responses that may require further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47393-4
Short code
Gliadin peptide IgA Ser Ql IA
Synonyms
Gliadin peptide IgA Ser Ql IA
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms like stomach pain, diarrhea, or unexplained weight loss, or if you have a family history of celiac disease. It can also be part of a screening process for gluten-related disorders.

What to Expect During Testing

A blood sample is taken from a vein in your arm. You may feel a small pinch, but it usually doesn’t cause discomfort. The test is quick and typically done in a doctor’s office or lab.

What the Results Mean

Positive results suggest an immune response to gluten, which may warrant further testing (like endoscopy or genetic testing) to confirm celiac disease or gluten sensitivity. Results alone don’t diagnose the condition.

Common Symptoms Linked to This Test

Symptoms like bloating, fatigue, skin rashes, or digestive issues may prompt this test. Some people have no symptoms but still test positive.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Role in Diagnosis

Short name

IgA Anti-Gliadin Antibody

Frequently asked questions

How often should I get this test?
This test is usually done as part of an initial screening, not routinely unless you have symptoms or risk factors. Follow-up testing may include additional bloodwork, genetic testing, or an intestinal biopsy.
Can I eat gluten before the test?
Yes, you can eat your normal diet before the test. The test measures your body’s response to gluten, not the gluten itself.
What if my test results are positive but I don’t have symptoms?
A positive result may indicate gluten sensitivity or celiac disease even without symptoms. Consult your doctor for further evaluation, such as genetic testing (e.g., HLA-DQ2/DQ8) or a gluten-free trial.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy