Serum IgG Anti-Gliadin Peptide Antibodies (Confirmatory)
This test measures the level of antibodies your immune system produces in response to gliadin, a protein found in gluten. It helps identify potential gluten sensitivity or celiac disease.
["This test supports diagnosing gluten-related conditions by detecting immune reactions to gluten."]
Key facts at a glance
- LOINC
- 63459-2
- Short code
- Gliadin peptide IgG Ser IA-aCnc
- Synonyms
- Gliadin peptide IgG Ser IA-aCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like persistent stomach pain, bloating, diarrhea, or unexplained weight loss. It may also be used as part of a broader evaluation for celiac disease, gluten sensitivity, or other gastrointestinal issues linked to gluten exposure.
What to Expect Before the Test
No special preparation is usually needed. You may have a blood sample drawn from a vein in your arm. If you’re on a gluten-free diet, your provider may ask you to temporarily reintroduce gluten before testing to ensure accurate results.
What the Results Mean
High levels of these antibodies may suggest an immune response to gluten, which can occur in conditions like celiac disease or non-celiac gluten sensitivity. However, they are not definitive on their own and may be used alongside other tests or clinical findings.
Common Symptoms Linked to High Antibody Levels
Symptoms like abdominal discomfort, digestive issues (such as diarrhea or constipation), fatigue, or unexplained weight changes might correlate with elevated antibody levels, but they don’t guarantee a diagnosis. Your provider will consider these results alongside your medical history and other tests.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated IgG anti-gliadin antibodies can indicate an immune reaction to gluten, which may be part of a broader diagnostic workup for celiac disease, gluten sensitivity, or other gluten-related disorders. While IgG antibodies alone are not diagnostic for celiac disease, they can help guide further testing or dietary adjustments.
Short name
IgG Anti-Gliadin Antibody Test
Frequently asked questions
What does a positive result mean?
Can I eat gluten before this test?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy