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Total Serum Protein 24-Hour Urinary Excretion Rate

Published: August 9, 2026Updated: August 16, 2026

This test measures how much protein is excreted in your urine over a 24-hour period. Protein loss in urine can indicate kidney problems or other health conditions.

Quick summary

["Assessing kidney function and detecting protein loss in urine over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15356-9
Short code
Globulin 24h Ur-mRate
Synonyms
Globulin 24h Ur-mRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like swelling, frequent urination, or signs of kidney disease. It helps track how much protein is being filtered through your kidneys and whether it’s being reabsorbed properly.

What to Expect Before the Test

No special preparation is needed. You’ll collect your urine for 24 hours in a container provided by your lab. Drink plenty of fluids to ensure accurate results.

How the Test Works

Your urine sample is analyzed to measure protein content. The test helps determine if your kidneys are retaining protein normally or if it’s being lost in urine, which can signal kidney damage or other conditions.

Possible Causes of Abnormal Results

High rates may indicate kidney disease, diabetes, or conditions like glomerulonephritis. Low rates might suggest dehydration or normal protein retention, but further evaluation is needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Protein Loss in Urine Can Signal Kidney or Systemic Issues

Short name

24-Hour Urinary Protein Rate

Frequently asked questions

How often should I collect urine for this test?
You’ll need to collect all urine for 24 hours, including at night. Use a clean container and mark the time each time you urinate to ensure accurate timing.
What if I miss any urine during the collection period?
If you miss urine, contact your lab or provider immediately to adjust the collection. Missing even small amounts can affect results.
Can diet affect this test?
Yes, high-protein foods or certain medications may influence results. Avoid excessive protein intake and consult your provider before changes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy